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Noteworthy, the detrimental effects of JNK are mostly attributed to the JNK1 isoform

doi: 10.1038/s41598-018-28559-8, 43

Ungprasert P, Crowson CS, Simonetto DA, et al
Although Lr GUS does not possess the NFXAA motif, we hypothesized that the EDD motif, which places three anionic side chains into the active site, precludes the entry of neutral substrates and may explain the poor p NPG processing activity of Lr GUS