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A multimodal approach to studying the relationship between peripheral glutathione, brain glutamate, and cognition in health and in schizophrenia

High performance liquid chromatography and mass spectrometry Synthetic GS-MQ or APR-246 treated de-proteinized JH-EsoAd1 cell lysates were resolved on an ODS-Hypersil C18 HPLC column (2.1 100 mm, 5 m, Hewlett-Packard) in 10 mM NH 4 HCO 3 pH 8, using a 080% acetonitrile gradient over 10 min

Upon activation, microglia maintain a balance between pro-inflammatory (M1-like) and anti-inflammatory (M2-like) phenotypes

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