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A slight decrease in appetite is possible but not universal

Pre-clinical studies suggest that low B12 may contribute to fat accumulation and disrupt lipid metabolism (how the body processes and uses fats for energy and storage)[1]

48 GLP-1 RA injectable agents in development for obesity treatment Survodutide Studied in a phase 2 randomized, double-blind trial in persons with pre-obesity and obesity (without diabetes) for 46 weeks
