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If human trials with the compound show safety and efficacy, NNMT inhibitors like 5-amino-1MQ could serve to prevent and/or slow age-related muscle deterioration in humans, a tantalizing prospect

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Full growth hormone administration can stimulate cortisol production through various mechanisms, and elevated cortisol is well-documented to increase appetite, particularly for high-calorie comfort foods, and promote abdominal fat accumulation

After the deficiency is fixed, injections might be needed only once a month