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Compared head-to-head with the powerful, FDA-approved GLP-1 medications which drive significant weight reduction by suppressing appetite AOD-9604 is simply less potent

Sources The Effectiveness of Cobalamin (B12) Treatment for Autism Spectrum Disorder: A Systematic Review and Meta-Analysis Journal of Personalized Medicine (2021) Vit B12 supplement of 500 g/d for eight weeks does not normalize urinary methyl-malonic acid or other biomarkers of vitamin B12 status in elderly people J Nutr

Decreases Food Cravings Cravings, emotional eating, and chronic hunger are common impediments to weight loss and healthy eating

These results established the 2.4mg dose as the primary research target