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Discussion In the present study, we confirm that Gsdmd cKO in SCs largely reduced the threshold elevation and OHC loss caused by noise exposure (2 h, 100 dB SPL), while no protection effect was observed in Gsdmd -HC-cKO mice

Blood pressure in treated hypertensive individuals with the MTHFR 677TT genotype is responsive to riboflavin

These distinct systems share the main activities for the formation of a [2Fe2S] cluster, which may be divided into three main stages: (1) Pyridoxal 5-phosphate-dependent cysteine (Cys) desulfuration with concomitant production of l-alanine, carried out by a cysteine desulfurase (CD)