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Additionally, ChaC1, by stimulating the GCN2/eIF2/ATF4 pathway, enhances necroptosis induced by cystine deprivation (54)

Mice deficient for Gsta4 are viable and appear phenotypically normal, but displayed increased susceptibility for bacterial infection 1,16
doi: 10.1186/s12931-019-1099-6 231

The processes of synthesis of the various lipid classes represent the most significant CoA-dependent reactions in the cell
