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Description
V.et al (2018)

The researchers found that the protein acetyl-L-carnitine was reduced in both men and women with mild cognitive impairment or early-stage Alzheimers and that free carnitine, a byproduct of acetyl-L-carnitine was reduced in women but not men with these conditions

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This gene variation negatively impacts carnitine transport across the blood-brain barrier (in males and not females), preventing the synthesis of a carnitine precursor called trimethyllysine
