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Thus, as we have more knowledge of the risk from the exposure to environmental pollutants, more well-designed epidemiological studies (controlling for as many variables as possible and with high sample sizes) are necessary to improve the quality of life of elderly and to prevent the development of neurodegenerative diseases worldwide

Known or suspected abuse of alcohol or recreational drugs

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In addition to their well-known anti-oxidative and anti-inflammatory capabilities, these natural products also play inhibitory roles in iron buildup, protein misfolding, the maintenance of proteasomal breakdown, mitochondrial homeostasis, and other neuroprotective processes