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Because VEGFR1 negatively modulates signalling through VEGFR2 (refs 21, 54) and ERK activation is a downstream effector of VEGFR2 signalling, we assessed pERK levels after Rab27a knockdown in endothelial cells and found a significant increase in both pERK and phosphorylated histone-H3, a mitosis marker downstream of ERK activation (Fig
Cellular Trafficking of Cell Stress Proteins in Health and Disease, series eds
Zinc is a crucial antioxidant and immune modulator that helps repair cell damage
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