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Upon activation, they undergo a metabolic switch from oxidative phosphorylation (OXPHOS) in quiescent states to aerobic glycolysis, a process essential for supporting proliferation, cytotoxic granule production (e.g., perforin, granzymes), and interferon-gamma (IFN-) secretion [10]

A novel anti-IL4R nanoparticle efficiently controls lung inflammation during asthma

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Yet, there are still many challenges ahead for preclinical studies and outstanding questions to address to move the field forward