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10.1210/EN.2008-0224 [DOI] [PMC free article] [PubMed] [Google Scholar] Omar M., Laknaur A., Al-Hendy A., Yang Q
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On the one hand, IL-1 exacerbates BBB disruption by downregulating tight junction protein Zonula Oc-cludens-1 (ZO-1), activating caspase-1 within the brain, and establishing a positive feedback loop that amplifies IL-1 production (36)
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