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It is believed that low CD38 expression is enough to initiate the intracellular signaling pathways since other receptors, such as NKG2D on KHYG1 cells, can compensate for the lack of CD38-mediated effector functions [63]
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European Commission grants marketing authorisation for Darzalex (daratumumab) subcutaneous formulation for all currently approved daratumumab intravenous formulation indications
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