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Some may cross the blood-brain barrier by the paracellular route, by transcytotic mechanisms, inside entering monocytes (the Trojan horse hypothesis), or by other mechanisms, such as hijacking of -adrenergic receptors, as done for example by N

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CCBE1 enhances lymphangiogenesis via a disintegrin and metalloprotease with thrombospondin motifs-3mediated vascular endothelial growth factor-C activation

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