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Description
They are frequently regulated at the transcriptional level via enhanced Nrf2 binding to ARE/EpRE DNA elements
In vivo, characterization of these small molecules supports that inhibition of STX7Munc13-4 binding and endosome maturation decrease eTLR-mediated systemic inflammation
A broad metabolic baseline is the appropriate starting point for anyone interested in evaluating any investigational compound's potential effects on their biology over time
doi:10.1158/1078-0432.CCR-10-3336
