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2025 May 28:775:152110

Consequently, a variety of anti-metabolic chemotherapy agents, including methotrexate and 5-fluorouracil, are widely utilized in clinical practice (3, 4)

The natural polyphenol curcumin provides broader neuroprotection

The exogenous pathway consists of the activation of cell membrane transporters for transferrin (TF) and lactoferrin (LF) or the inhibition of cystine/glutamate (CySS/Glu) antiporters, while the endogenous pathway is the inhibition of GPX4 activation within cells (Li J
