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GHK-Cu is considered safe for topical use in most individuals

10.1038/s41598-018-30428-3 Sci

Peroxides, such as H 2 O 2 can trigger a two-electron oxidation of Hb leading to the formation of ferryl (Fe 4+ = O 2 ) Hb (Table 1, equation 2), whereas the reaction of metHb with H 2 O 2 yields ferrylHb radical (Hb + (Fe 4+ = O 2 )) in which the unpaired electron is associated with the globin or the porphyrin ring (Table 1, equation 3) (Harel and Kanner, 1988