glutathione peroxidase 1a Validated Applications The Role of Glutathione Peroxidase-1

It is characterized by progressive neurodegeneration, developmental delay, muscle weakness, respiratory problems, optic atrophy, and other symptoms such as seizures and feeding difficulties

However, harmful substances can also be synthesized by gut microorganisms, emphasizing the need for small molecule inhibitors to regulate specific transformations

Indian J Pharmacol 36(3):148 Cheenpracha S, Park E-J, Yoshida WY, Barit C, Wall M, Pezzuto JM, Chang LC (2010) Potential anti-inflammatory phenolic glycosides from the medicinal plant Moringa oleifera fruits

Conclusion By focusing on the ROS-related PIPN mechanism, both antioxidant drugs (e.g., small molecular drugs, traditional medicines/active ingredients) and tailor-made nanosystems (e.g., tumor-targeting Pt nanosystems and anti-ROS nanosystems) have demonstrated to be effective in the prevention and treatment of PIPN