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In a clinical trial of 71 women with mild to advanced photoaging, a GHK-Cu facial cream applied daily for twelve weeks significantly increased skin density and thickness while reducing fine lines, wrinkles, and laxity
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In the adrenal glands, their activation stimulates the release of aldosterone that in turn promotes sodium reabsorption in the mineralocorticoid-responsive segments of the distal nephron (Masilamani et al., 1999)
