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Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension

doi: 10.1007/s12012-023-09804-7 72 RyanFBlexCNgoTDKoppMAMichalkeBVenkataramaniVet al

Renal OCTN2 expression and activity increase when the carnitine concentration is reduced in the plasma and/or glomerular filtrate, whereas OCTN2 mRNA expression levels remain unchanged in the gut, liver, or skeletal muscle [254], highlighting the central role of the kidney in maintaining carnitine homeostasis
