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Due to its high solubility, amphipathic structure, and low molecular weight, melatonin displays a high intracellular and extracellular diffusion capacity, being able to cross cell membranes and the blood-brain barrier [6,15]

This approach forms a key part of a NMT treatment plan for managing diabetic neuropathy symptoms, encouraging healing while supporting nerve and vascular health in the lower extremities

This process involves the use of immobilized metal ion affinity chromatography with mass spectrometry in surface-enhanced laser desorption/ionization (SELDI)

These findings suggest that NAC exerts a cytoprotective effect by mitigating mercury-induced oxidative damage and inflammation in lung tissue
