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Reprogrammed transsulfuration promotes basal-like breast tumor progression via realigning cellular cysteine persulfidation

10.1038/s41467-023-43719-9 [DOI] [PMC free article] [PubMed] [Google Scholar] 22.Cohrs CM, Panzer JK, Drotar DM et al (2020) Dysfunction of persisting cells is a key feature of early type 2 diabetes pathogenesis

DSIP, Pinealon, and Epitalon are studied across overlapping laboratory models involving neuropeptide signaling, pineal pathway biology, circadian rhythm systems, CNS response models, oxidative stress biology, and cellular aging pathway research

Together, these cell-type-specific ferroptotic events converge to produce the core pathological features of depression: hippocampal shrinkage, disrupted neurogenesis, and impaired prefrontal cortical function, ultimately driving the clinical manifestations of anhedonia, executive dysfunction, and persistent low mood (Troubat et al., 2021