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Subsequently, the monocytes differentiate into macrophages that regulate various healing processes (Huang et al., 2020)

Therefore, there is an attempt to induce methyl deficiency through feed additives, such as guanidinoacetic acid (GAA), to better evaluate the role of RPM in supporting methyl donor supply

GPX4 uses the cofactor glutathione to scavenge reactive oxygen species (ROS) in the cell membrane, cytosolic and mitochondrial compartments

These agents mitigate airway hyperreactivity, inflammatory infiltration, and remodeling through potent lipid radical scavenging (162)
