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Description
55 JNK signaling pathway JNK, a subgroup of the mitogen-activated protein kinase (MAPK) family, can be activated by the inflammatory factors, metabolites and the crosstalk between other signaling pathways

Epigenetic dysregulation has emerged as one of the transcriptional vulnerabilities in human cancer

Javitt DC, Steinschneider M, Schroeder CE, Arezzo JC (1996)

e , Schematic showing how the iron-sulfur cluster-containing protein LIAS enables OGDH and PDH activity by transferring lipoic acid as a cofactor to their enzyme complexes (left)
