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178 In addition, it was found that TRPV1 genetic deletion, inhibition, or desensitization in mice decreased the activity of osteoclasts in vitro and inhibited ovariectomy-induced bone loss as well as osteoporosis in vivo

4a, the GhGPX1 gene encoding a putative chloroplast protein not only showed expression pattern in roots, stems, flowers, leaves and cotyledons, but was also with most strongly expression level in flowers, and high transcript level in leaves

Therefore, we reasoned that PrP might stimulate Cu uptake and, thereby, toxicity in ATP7B-deficient cells, while PrP suppression could counteract this process

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