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2B, G6PD, TrxR1)

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Inhibition of carbonic anhydrase in the ciliary body (located behind the iris and is responsible for the production of the aqueous humor inside the eye) decreases the aqueous humor secretion resulting in a lower of the intraocular pressure

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Superoxide anion is converted into H 2 O 2 through enzymatic and nonenzymatic dismutation processes (Fridovich 1989)

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On the contrary, Ucp2 KD treatment aggravated oxidative stress, autophagy, and mitochondrial fragmentation

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