glutathione pathway breast cancer Metabolism in Renal Cell Carcinoma Progression and Implications for Therapies reduced glutathione and breast cancer

T.et al (2006)

In this review, we discuss how selenium availability and modifiers of selenocysteine incorporation alter GPx1 expression to promote disease states

GSH AS A PHYSIOLOGICAL MODULATOR OF NO HOMEOSTASIS The importance of GSH in protecting the electron transport chain from ONOO - is illustrated by experiments with GSH depleted astrocytes

"It is likely that dietary compounds that are not essential for survival and are used exclusively for protecting and improving healthy longevity would not yet have been recognized as a vitamin or mineral, because the effects of their deficiency would have been evident only in the form of insidious late damage." For skin specifically, this framing matters