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Interestingly, S6K inhibition in the hepatocytes did not block the induction of Srebp-1c mRNA in response to insulin but did impair insulin-stimulated processing and activation of SREBP-1c, suggesting that downstream of mTORC1, S6K regulates DNL at the protein expression level (189, 245)
Updates in the Impact of Chronic Systemic Inflammation on Vascular Inflammation by Positron Emission Tomography (PET)
Free Radic Res.2007;41(8):884-891
