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Its pharmacological effects stem primarily from the disruption of monoaminergic neurotransmission and its downstream neurotoxic consequences

As a tropane-derived compound, Tesofensine represents a research subject in the broader field of small molecule structure-activity research
Although not contraindicated, clinicians should closely monitor thyroid function tests and adjust therapy as weight and metabolic status evolve under GLP-1RA treatment [65]

[DOI] [PMC free article] [PubMed] [Google Scholar] 58.Aihara M