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This support previous works that showed a disruption of Wnt proteins by neonatal exposure to GBH (2 mg/kg bw/day) from PND1 to PND7, in rat uterus (PND21) and implantation sites (GD9) ( Table 1 )

The discovery of active receptors in porcine testis and in bovine spermatozoa cells has ratified the action of GH and IGF-1 on sperm cells [88]

10.1021/acs.jmedchem.0c01671 41

SIRT1 interacts with TSC2, a key enzymatic component of the TSC complex, to inhibit mTORC1 signaling (Ghosh et al., 2010)