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Biomedicine and Pharmacotherapy

As a consequence, exposure of human spermatozoa to intrinsically- or extrinsically- generated reactive oxygen intermediates can result in a state of oxidative stress characterized by peroxidative damage to the sperm plasma membrane and DNA damage to the mitochondrial and nuclear genomes

This ENS damage is a primary reason SIBO recurs after treatment a damaged ENS produces impaired MMC function, which allows bacterial recolonisation
