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Additional observed toxic mechanisms included loss of MMP, upregulation of the proapoptotic protein Bcl-2-associated X protein (BAX), and downregulation of antiapoptotic markers such as B-cell lymphoma 2 (Bcl-2), poly ADP ribose polymerase (PARP), and caspase-3 [134]

Its job is to improve the environment for healing by supporting circulation, tissue recovery signaling, and the metabolic capacity of injured tissue

It binds to the 50S ribosomal subunit, preventing the formation of the functional 70S initiation complex required for translation (Leach et al., 2011
