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The exclusion criteria eliminated studies that were not directly related to PD pathophysiology or therapeutic applications
In response to different activating stimuli, Nrf2 is stabilized and translocates to the nucleus, where it activates the transcription of its downstream targets (49, 117)
Glutathion S-transferases (GSTs), an eukaryotic and prokaryotic phase II metabolic isozymes-family, catalyze the conjugation of reduced form of gluthatione (GSH, nucleophil) and xenobiotics (electrophil) to gluthatione-S-Conjugate via nucleophilic attack (see Figure 4)
10.1016/j.rmed.2016.06.015 Respir
