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this interaction is required for oxidative burst (Sarfstein et al., 2004

(C-D) Protein expression and quantitation of PINK1, Parkin, Beclin1, p62, LC3 I/II, ATG5, and ATG7 were determined by western blotting in the intestinal mucosa of piglets

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Arachidonic acid 12 lipoxygenase (ALOX12) is also closely associated with p53-mediated ferroptosis ( TP53-induced glycolysis and apoptosis regulator (TIGAR) is a target gene of p53 that inhibits cancer and has an antioxidant effect ( p53 can also promote ferroptosis by influencing the function of ferredoxin reductase (FDXR) in iron metabolism (Zhang et al., 2017)