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However, a secondary analysis revealed that replacing beta-carotene with lutein and zeaxanthin led to significant benefits, including an 18% reduction in the risk of advanced AMD progression and a 22% decrease in neovascular AMD risk [122]

Zou H., Gong L., Wang Z., et al., Effects of Trimethylamine NOxide in Improving Exercise Performance in Mice: A 1HNMRBased Metabolomic Analysis Approach, Molecules (Basel, Switzerland) 29, no

Common side effects include drowsiness, dizziness, headache, tremors, weight gain, nausea, vomiting, diarrhea or constipation, and hair loss

In hepatocytes, depleted mtDNA impairs mitochondrial function, contributing to hepatic steatosis and further liver injury