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Moreover, NQO1 has been shown to modulate the redox state of various transcription factors, such as p53, AP-1, and Nrf2, thereby influencing the expression of diverse genes implicated in cell cycle control, apoptosis, and antioxidant defense

[DOI] [PMC free article] [PubMed] [Google Scholar] Brown SW, Meyers RT, Brennan KM, Rumble JM, Narasimhachari N, Perozzi EF, Ryan JJ, Stewart JK, Fischer-Stenger K (2003) Catecholamines in a macrophage cell line

Another study showed that antagonists of 9-containing nAChRs are analgesic in animal models of neuropathic pain (Hone et al., 2018)

Heavy Metal Exposure and Elimination Heavy metals are eliminated by the body via different mechanisms, which rely heavily on our bodys metallothionein and glutathione systems