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Importantly, their role in IR is not unidirectional: their pro-inflammatory outputs can impair adipocyte insulin sensitivity, yet their clearance of dead cells and debris can limit tissue-level inflammatory amplification during adipose remodeling and hepatic steatosis

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However, as with any emerging field, there are currently several different methods for collection, processing, storage, and calculation of summary measures of plasma glutathione metabolism, within and between preclinical and clinical research