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To validate the 48-h run-in diet, a coefficient of variation (CV) in baseline plasma TMAO was calculated across three fasting measurements (Phase I baseline, Phase II intervention 1 baseline, and Phase II intervention 2 baseline)

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6.4 Emerging evidence on combinatory interventions in elderly populations Emerging clinical evidence substantiates the translational potential of integrating these interventions within geriatric cohorts

It has also been shown that ALC can be used as an alternative substrate in mitochondrial respiration in the absence of pyruvate [12]