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Increasing awareness, facilitating comprehensive evaluations, and supporting dedicated research initiatives are essential steps toward a deeper understanding and more effective management of male infertility

Chem, 2017, 89, 1063910643

In addition, ozone therapy exerts a regulatory effect on key transcription factors: it activates Nrf2, endorsing antioxidant and anti-inflammatory responses, while concurrently inhibiting NF-kB, integral in inflammation regulation [18, 33, 35, 36]

This may lead to a decrease in the generation of liquid waste that contains the nitrate ester, an energetic material, and, thus, disposal costs and overall operating costs for the production of the nitrate ester may be reduced