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4 As NCDs are the leading cause of death worldwide, 3 , 5 it is utterly important to focus on reducing the risk factors associated with these diseases
The various glucose-modified PIC/Ms improved brain by-products owing to their multivalent interaction with GLUT1 located on the brain capillary endothelial cells (109) siRNA loaded magnetic nanoparticles have been effectively used as delivery mechanisms for targeting microglia in AD to reduce neurodegeneration (110)

In addition, once MODS develops, the gut is continuously injured by a combination of factors intrinsic to critical illness (dysbiosis, ischemia, etc.) and unintended consequences of interventions not aimed at the gut but that injure components of the gut (proton pump inhibitors, antibiotics, opioids, etc.)
Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes
