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doi: 10.1186/1750-1326-9-25
found SUMO-specific proteases 1 (SENP1) expression was decreased in IH-treated microglia, which reduced the level of Target of Myb 1 (TOM1) and peroxisome proliferator-activated receptor (PPAR) by promoting their SUMOylation, and aggravated neuroinflammation and neuronal apoptosis [97, 98]
Kim S-K, Kassis J, Attucks O, Zhong Z, Freeman J, Gupta S, et al

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