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Importantly, the FAP + fibroblast population decreased significantly in the CD5/ LNP group, whereas PFD treatment had no effects on this indicator (Fig

Havervall S, Rosell A, Phillipson M, et al

Pathology emerges focally and in discrete patches in the sulci of the neocortex, oftentimes in the superior and dorsolateral prefrontal cortex, but increasing in prevalence and spreading to temporal and parietal cortices as the degeneration progresses

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