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Article highlights: CYP2D6 is estimated to contribute to the metabolism of approximately 2025% of drugs

Statistical analyses were performed using SPSS software (ver

The secondary effects of metformin have been attributed to the activation of the metabolic regulator AMP-activated protein kinase and the potent antioxidant enzyme peroxiredoxin-2 [454]

Always consult your healthcare provider if you have any concerns.
