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Moreover, few studies have investigated off-target activation in normal tissues where GSH levels may still be substantial (e.g., liver, kidney)

We observed the dissociation of p53 TAD (13-61) from FOXO4 FHD upon the addition of p53 TAD PEP, resulting in a chemical shift of the 15 N-p53 TAD-FOXO4 FHD complex towards the unbound state of p53 TAD (Figure

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