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Zeng D, Liang YK, Xiao YS, Wei XL, Lin HY, et al

found patterning signals like Shh expression were downregulated over time while expression of synthetic genes like TGF- and insulin growth factor (IGF) were upregulated in the same developmental window, providing insights into gene families required for patterning, ECM synthesis, and maintenance of the NP

The key point is that homocysteine should not be interpreted in isolation

This regulatory gene, named SlZF3 , encodes a Cys2/His2type zincfinger protein, which contains an EAR repression domain
