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We discuss evidence for a causal role of immune mechanisms in the pathogenesis of depression, together with targets under investigation in randomized controlled trials, biomarker evidence elucidating the link to neural mechanisms, biological and phenotypic patient selection strategies, and the unmet clinical need among patients with MDD

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Long-Term Use of GLP-1 Medications For many patients, GLP-1 medications become a long-term part of their treatment plan