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In addition, we found a T cell cluster characterized by the presence of Leishmania transcripts (Leish + ), which presumably results from the incorporation or attachment of parasite mRNA through interactions with (debris or extracellular vesicles of) infected cells, although endocytosis of Leishmania amastigotes by (activated) T cells cannot formally be excluded (Wu et al, 2009)

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Upregulation of tissue factor on monocytes and other cells or endothelial injury exposing tissue factor would also trigger DIC in dogs with IMHA by activating factor VII (Kidd et al 2015)