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4 Function of curcumin in the treatment of specific NDs 4.1 Alzheimers disease 4.1.1 Pathogenesis of AD Alzheimers disease (AD) is a progressive neurodegenerative disorder that accounts for 60%80% of all dementia cases worldwide

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The presence of Akkermansia muciniphila , known to modulate BA metabolism, has also been associated with enhanced PD-1 blockade efficacy in MAFLD-related HCC, suggesting its potential as a predictive biomarker (50)

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