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A map of general and specialized chromatin readers in mouse tissues generated by label-free interaction proteomics

To confirm the phenotype changes were driven by OGDHc inhibition, we also treated cells with DM-2OG, mimicking impaired 2-OG metabolism by the OGDHc, and found that, similarly to ML226, DM-2OG increased the CCR7 high CD45RO high population, with a corresponding decrease in the CCR7 low CD45RO high population (Fig
Treatment with polyethylene glycol-conjugated fungal D-amino acid oxidase reduces lung inflammation in a mouse model of chronic granulomatous disease

Research has identified effects on blood vessel formation, growth factor expression, nitric oxide production, and cellular signaling cascades
