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Keywords: L-carnitine, acetyl-L-carnitine, neuroprotection, neonatal hypoxia-ischemia, pediatric traumatic brain injury, metabolism, inborn errors of metabolism, carnitine shuttle Introduction L-Carnitine is a naturally occurring compound found in most, if not all, mammalian tissues including brain [1]

Thus, its use in MELAS is well-documented.8,14,15 Nucleotides and 3 fatty acids are other important components of immunonutrition in critically ill patients.11,12 Nucleotides are essential for the synthesis of RNA, DNA and energy-transporting molecules

Carnitine: metabolism and functions

It is characterized by severe disabling fatigue and a spectrum of symptoms highlighted by self-reported attention and short-term memory impairments, sleep disturbances, and musculoskeletal pain